NIH Proteomics Interest Group

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ProtIG is an NIH Special Interest Group (SIG) that organizes seminars and workshops in relevant areas of proteomics, including talks on separation and protein identification methods, determination of post-translational modifications, protein-protein interactions, and bioinformatics and data management. A monthly seminar series is usually held at 10 am on the Second Thursday of each month (always check the Mtgs/Seminars button on this page for these and other PROTIG announced meetings). To receive email announcements of ProtIG events, join the listserv (Join the SIG button on this page)

October ProtIG Seminar
Thursday October 10th, 2019
10:00 am - 11:00am
Building 50, NIH Campus
Room 1328/1334 (Rear Lobby Conference Room)
Benjamin Orsburn, Ph.D.
Senior Proteomics Scientist
University of Virginia Medical School


"Constructing Multi-Omics Draft Maps of Organisms without Annotated Genomes: Example Cannabis sativa"

Due to legal restrictions, very little science has been performed on Cannabis plants in the U.S. and these restrictions did not lessen until the passage of the 2019 Hemp Act. These limitations are apparent in the fact that less than 300 annotated proteins are available in public repositories. To aid the development of this new field, we have begun construction of a multi-omics "draft map" of Cannabis plants. By integrating high depth proteomics with publicly available "next generation" long read and short read sequencing output we have created a resource that now contains quantitative information on 13,850 annotated proteins. Our pipeline utilizes peptide spectral matches as a quality control filter for genomics data and allows for the construction of annotated protein files using standard desktop computers and online web interfaces. Furthermore, by integrating global metabolomic characterization of materials we present a simple method by which proteins/gene products are ranked in order of statistical likelihood in the involvement of production of secondary metabolites. All data for this study is publicly available at www.CannabisDraftMap.org





This seminar will not be videocast


Seminars will be webcast online at http://videocast.nih.gov and available on the
Proteomics Interest Group website http://proteome.nih.gov as an archived presentation unless otherwise noted.



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This site was updated on September 30th, 2019. Please contact Renee Olano at olanol(at)mail.nih.gov with questions or suggestions.