ProtIG is an NIH Special Interest Group (SIG) that organizes seminars and workshops in relevant areas of proteomics, including talks on separation and protein identification methods, determination of post-translational modifications, protein-protein interactions, and bioinformatics and data management. A monthly seminar series is held in the Building 50 1st floor conference room at 10am on the first Friday of each month (always check the Mtgs/Seminars button on this page for these and other PROTIG announced meetings). To receive email announcements of ProtIG events, join the listserv (Join the SIG button on this page)

ProtIG First Friday Seminar Series

May 23, 2008

10am - 11am

Building 50, NIH Campus

1st Floor Auditorium

Klaus Hahn, Ph.D.

University of North Carolina

"Dynamics of macromolecular complexes in living cells: Multiplex imaging of signaling activities, genetically encoded protein uncaging, and RapR-FAK"

This talk will describe approaches to study and manipulate multiple nodes of a signaling pathway in living cells, revealing unexpected relationships between Rho family GTPases in motility. New methods for spatially and temporally controlled manipulation of protein activity will be described, including genetically encoded caged Rac, and Fak activated by drug treatment. These approaches may provide generally applicable tools to study signaling pathways in living cells.

First Friday Seminars will be webcast online at http://videocast.nih.gov/ and available on the Proteomics Interest Group website http://proteome.nih.gov as an archived presentation.

This site was updated on April 29, 2008. Please contact Leticia Cano at canol@nhlbi.nih.gov with questions or suggestions.